Highway 66 is a north-south highway in the Jezreel Valley in northern Israel. It extends along the eastern lowlands below the Menashe Hills and the Carmel. It is 20 km long. In the past the road continued south to Jenin, but today it ends at Ta'anakh junction.
| Kilometers | Name | Location | Intersecting routes | |
|---|---|---|---|---|
| Highway 66 | ||||
| 0 | Ta'anakh junction | Ti'anikh | Route 596 (Israel) | |
| 6 | Megiddo junction | Megiddo (kibbutz) | Highway 65 (Israel) | |
| 13 | Mishmar Ha'Emek junction | Mishmar Ha'Emek | Route 6953 | |
| 20 | HaTishbi junction | Yokneam | Highway 70 (Israel), Route 722 | |
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